Celsion, an oncology drug development company, spoke in detail about a development that could play greatly into the studies of brain cancer. It would set its sights primarily on glioblastoma, which is understandable when given the details. Often regarded as the most aggressive form of cancer in the brain, it's not hard to see why this is such a big focus. That being said, is it possible that a new approach can be put to use in order to help patients who have been impacted by the condition in question?
It seems like there is the possibility for this to happen, as an article on Pharmaceutical Business Review detailed. With a certain approach brought into effect, the goal is to help treat tumors in the brain, with glioblastoma being the primary focus. While it's clear that this ailment has been given focus by organizations such as Voices against Brain Cancer, one has to wonder what exactly this approach entails. There are a couple of elements that can help to bring this approach together and allow it to be successful.
The company will put forth experiments that will determine the effectiveness of ThermoDox in conjunction with MR guided high intensity focused ultrasound. The focus will be placed on animal models first before, if successful, being parlayed into human use. According to Dr. Nicholas Borys, ThermoDox is a "heat-activated liposomal encapsulation of doxorubicin," which would be able to provide clinical benefit. It has also been utilized for the sake of treating other types of cancer, which lends credence to the idea that it could come into play in this field as well.
The report spoke about a phase III HEAT study that has been done in order to test the effective of ThermoDox in addition to RFA. The study was conducted in order to see how well patients would react to this particular combination. From what I have gathered by the results, ThermoDox could actually work well in order to improve PFS, provided that that the lesions of patients undergo RFA for around 45 minutes. As it stands, positive results are to be seen in this regard.
It's apparent that there are a number of results to take into account when talking about ThermoDox. The approach seen here is one that houses tremendous potential and the fact that it has been utilized to help other forms of cancer should not be overlooked. Liver cancer, for instance, has been focused on, so it's apparent that there is a level of versatility to be seen here. In my opinion, this goes to show that brain cancer can be made that much better because of ThermoDox.
It seems like there is the possibility for this to happen, as an article on Pharmaceutical Business Review detailed. With a certain approach brought into effect, the goal is to help treat tumors in the brain, with glioblastoma being the primary focus. While it's clear that this ailment has been given focus by organizations such as Voices against Brain Cancer, one has to wonder what exactly this approach entails. There are a couple of elements that can help to bring this approach together and allow it to be successful.
The company will put forth experiments that will determine the effectiveness of ThermoDox in conjunction with MR guided high intensity focused ultrasound. The focus will be placed on animal models first before, if successful, being parlayed into human use. According to Dr. Nicholas Borys, ThermoDox is a "heat-activated liposomal encapsulation of doxorubicin," which would be able to provide clinical benefit. It has also been utilized for the sake of treating other types of cancer, which lends credence to the idea that it could come into play in this field as well.
The report spoke about a phase III HEAT study that has been done in order to test the effective of ThermoDox in addition to RFA. The study was conducted in order to see how well patients would react to this particular combination. From what I have gathered by the results, ThermoDox could actually work well in order to improve PFS, provided that that the lesions of patients undergo RFA for around 45 minutes. As it stands, positive results are to be seen in this regard.
It's apparent that there are a number of results to take into account when talking about ThermoDox. The approach seen here is one that houses tremendous potential and the fact that it has been utilized to help other forms of cancer should not be overlooked. Liver cancer, for instance, has been focused on, so it's apparent that there is a level of versatility to be seen here. In my opinion, this goes to show that brain cancer can be made that much better because of ThermoDox.
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If you'd like further details about glioblastoma, please consult Voices against Brain Cancer.. This article, A Potential Development Program To Help Glioblastoma is available for free reprint.
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